The aim of this study was to investigate the cytotoxic, genotoxic, mutagenic, and protective effects of 2hmc using the ames mutagenicity test, the mouse bone marrow micronucleus test, and the. Most of the time the term cytotoxic refers to the effect that a there is much confusion between the terms cytotoxic and genotoxic the term cytotoxic refers to the ability of a substance to cause damage to cells the term genotoxic refers to the ability of a substance to directly damage dna in cells. Many studies have reported the genotoxic and cytotoxic effects of artemisinins however, there are no studies that compare such effects between cancer cell lines and normal human cells after treatment with artemether, an artemisinin derivative. In this study, the genotoxic and cytotoxic potentials associated with exposure to chloroform and eucalyptol were assessed on mouse lymphoma cells in vitro by the single cell gel (comet) assay and trypan blue exclusion test, respectively. Cytotoxic: toxic to cells, cell-toxic, cell-killing any agent or process that kills cells chemotherapy and radiotherapy are forms of cytotoxic therapy they kill cells the prefix cyto- denotes a cell it comes from the greek kytos meaning hollow, as a cell or container toxic is from the greek.
Investigations of cytotoxic or genotoxic effects of emf on other cells lines include blood cells and immune cells previous investigations of comet assay, sister chromatid exchanges, and chromosome aberrations along with micronucleus tests were also conducted to study genotoxic effects of elf-emf on blood cells. Cytotoxic and genotoxic effects of titanium dioxide nanoparticles in testicular cells of male wistar rat ramovatar meena & kumari kajal & paulraj r received: 6 february 2014/accepted: 15 october 2014 . Genotoxic and antigenotoxic effects were evaluated with a comet assay and micronuclei on binucleated cells results: five of nine horchatas had cytotoxic effects against d-384 while not affecting normal cells.
The genotoxic effects observed suggest that traditional folk medicines prepared from extracts of the immature fruit of a montana should be used with caution cytotoxic and genotoxic effects of extracts from annona montana m fruit: food and agricultural immunology: vol 27, no 4. Cytotoxic, apoptotic and genotoxic effects of lipid-based and polymeric nano micelles, an in vitro evaluation fatemeh bahadori 1, abdurrahim kocyigit 2, , hayat onyuksel 3 , aydan dag 4 and gulacti topcu 1 1 department of pharmaceutical biotechnology, faculty of pharmacy, bezmialem vakif university, fatih, istanbul 34093, turkey. Generally and depending on the agent, a cytotoxic agent may be genotoxic (causing dna damage), mutagenic (causing gene mutation) or it may be harmful for cell organelles (eg cell membrane) or it.
Cytotoxicity is the quality of being toxic to cellsexamples of toxic agents are an immune cell or some types of venom, eg from the puff adder (bitis arietans) or brown recluse spider (loxosceles reclusa. Research paper cytotoxic and genotoxic effects of perﬂuorododecanoic acid (pfdoa) in japanese medaka isaac o ayanda1,2,, min yang2, zhang yu2 and jinmiao zha2 1 department of biological sciences, covenant university, ota, ogun state, nigeria 2 state key laboratory for environmental aquatic chemistry, research center for eco-environmental sciences, beijing, china. 147 genotoxic and cytotoxic effects of antibacterial drug, ciprofloxacin, on human lymphocytes in vitro ps ambulkar,1 sk ghosh,2 iv ingole3 and ak pal3 1department of biotechnology,agnihotri college of science, wardha-442001, india 2department of anatomy, nepal medical college, jorpati, kathmandu, nepal 3human cytogenetics unit, department of anatomy, mahatma gandhi institute of medical. Cytotoxic drugs have also been associated with negative health effects for developing fetuses, including higher incidences of spontaneous abortions, congenital malformations, low birth weight, and infertility.
The plymouth student scientist, 2017, 10, (1), 41-63  the cytotoxic and genotoxic effects of bisphenol a on neuronal cells in vitro shannon o’sullivan. The genotoxic and cytotoxic effects of a widely used herbicide, fluchloralin, were assessed using cultured mammalian cells treatment of cells for 8-12 hr with fluchloralin resulted in a significant increase in the frequency of metaphase cells with chromosomal damage. The genotoxic and mutagenic effect of kalanchoe laciniata to access the safety and usefulness of the medicinal plant aqua-methanolic and n-hexane extracts of k laciniata were evaluated for the genotoxic potential using.
The aim of this study was to investigate cytotoxic and genotoxic effects of aqueous extracts (40, 80 and 120 g/l) from l stoechas flowers on allium cepa root tip meristem cells for this purpose, a cepa onion bulbs were treated with the above-mentioned l stoechas flower extracts for 72 h spring water (ph 73) was used as a control. The cytotoxicity and genotoxicity of abamectin, chlorfenapyr, and imidacloprid have been evaluated on the chinese hamster ovary (chok1) cells cytotoxic and genotoxic effects of abamectin, chlorfenapyr, and imidacloprid on cho k1 cells authors authors and affiliations bañuelos-ruíz e (2012) evaluation of genotoxic and cytotoxic. Situations that elevate plasma levels as renal conditions or even administration or prescription errors can bring cytotoxic and genotoxic consequences beyond the adverse effects inherent to their own use.