Prevalence of h pylori isolates and genotypes and caga gene

Chichaklu a h, hedayati m a, esmaili f s, ghaderi e, shiri m h d prevalence of hopq alleles and relationship between caga and vaca s1 with hopq i gene in helicobacter pylori strains isolated from patients with peptic ulcer referred to towhid hospital in sanandaj (2014. Resistant mutations such as a2143g, a2142g, a2142c in 23s rrna gene of h pylori-positive patients was determined using a real-time pcr allelic discrimination assay results: h pylori was detected in 41 (398%) biopsies and, out of these, 17 (415%) tested positive for the caga gene. Prevalence of helicobacter pylori vaca, caga, cage, helicobacter pylori, prevalence, genotypes, gastrointestinal diseases previous studies reported that the vaca genotype and occurrence of the caga gene varied in h pylori isolates collected from different parts of the world.

Caga-positive h pylori isolates are associated with a higher rate of gastric inflammation and damage, when compared with caga-negative strains[8 9] the caga gene is located at the end of the cag pathogenecity island, a system that introduces caga and a peptidoglycan into epithelial cells[ 10 . That have observed a higher prevalence of h pylori h pylori isolates from different samples presence of the icea1, icea2, oipa, caga, baba2 genotypes and also various genotypes of vaca alleles (s1a, s1b, s1c, m1a, m1b and m2) were determined using pcr technique. Mine the prevalence of h pylori isolates in patients with a full spectrum of clinical manifestations of h pylori infection to evaluate whether the postulated associations with vaca genotypes and caga gene would be applicable to patients with h pylori infection in iranian populations materials and methods.

H pylori isolates with positive oipa had may be contributed to presence of different type of the caga and effect of other confounding factors rather than the caga the prevalence of the cage gene is also diverse shb rabenhorstprevalence of helicobacter pylori genotypes (vaca, caga, cage and virb11) in gastric cancer in. Prevalence of helicobacter pylori vaca, caga, the 349-bp pcr product indicating the presence of the caga gene was obtained with 173 isolates (616%) and 108 (384%) no difference in prevalence of caga genotypes was found between peptic ulcers and other gastroduodenal diseases. Furthermore, this is the first study to reveal a high prevalence of the oipa gene in h pylori isolates in brazil gastric diseases such as chronic gastritis and gastric cancer are most commonly caused by virulence factors of helicobacter pylori (h pylori), such as the vaca, caga, dupa and oipa genes. The aim of this study was to examine the genotypes of h pylori strains, vaca, caga and icea, using pcr based methods, in patients from the eastern cape province of south africa, which is a predominantly rural region, a predisposing factor for h pylori acquisition furthermore, this study is expected to provide baseline information for future. The aim of this study was to investigate the prevalence of the vaca, caga, cage, icea, baba2 and oipa genotypes of h pylori isolates from patients with upper gasterointestinal problem or dyspepsia.

The icea1 genotype was present in 947% and 864% of isolates from duodenal ulcer and non-ulcer dyspepsia patients, respectively caga + infection was found predominantly (90%) in nigerian h pylori isolates irrespective of the clinical diagnosis. Ozbey, g and aygun, c h pylori genotypes the caga gene being a marker for the presence of the cag pathogenicity island (cagpai) of approximaely 40 kb was the first gene found to be present in h pylori strains (7) and its presence is associated with a more severe clinical outcome. This study was carried out to investigate the prevalence of cytotoxin associated gene a (caga) and blood adhesion binding antigen (baba2) genotypes of h pylori isolates from egyptian patients and its correlation with the sensitivity to antibiotics included in triple therapy.

Caga-positive h pylori isolates are associated with a higher rate of gastric inflammation and damage, when compared with caga-negative strains[8,9] the caga gene is located at the end of the cag pathogenecity island, a system that introduces caga and a peptidoglycan into epithelial cells[ 10 . Erzin y, koksal v, altun s, dobrucali a, aslan m, erdamar s et al (2006) prevalence of helicobacter pylori vaca, caga, cage, icea, baba2 genotypes and correlation with clinical outcome in turkish patients with dyspepsia. Given that h pylori pathogenicity-associated factors in isolates from different populations have been shown to possess distinct genotypes [16 – 18], it is important that the association between a newly identified putative pathogenicity-associated factor, such as dupa and specific disease outcomes, be assessed in clinical isolates from a. The caga is a marker for the genomic pathogenicity island of c 40 kb [cag pathogenicity island (cag-pai)] and its presence in western h pylori isolates has been shown to be strongly associated with peptic ulcer disease (yamazaki et al, 2005.

  • The purpose of this study is to identify the prevalence of h pylori isolates in patients with a full spectrum of clinical demonstration of h pylori infection to evaluate whether the assumed associations with genotypes and caga gene would be applicable to patients with h pylori infection in malaysian populations.
  • According to the uncertain role of foods in the transmission of h pylori to humans, as well as based on the lack of epidemiological and microbiological researches in this field in iran, the present study was done in order to assess the prevalence rate and genotyping of vaca and caga alleles of h pylori strains isolated from raw meat, milk.

The aim of this study was to investigate the prevalence of the vaca, caga, cage, icea, baba2 and oipa genotypes of h pylori isolates from patients with upper gasterointestinal problem or dyspepsia material and methods h pylori isolated from endoscopic biopsies obtained from 222 studied patients. The geographical variation in helicobacter pylori genotypes is an observed phenomenon cytotoxin associated genes a ( caga ) and e ( cage ), and vacuolating cytotoxin ( vaca ) genotypes of h pylori are associated with peptic ulcer disease (pud. We evaluated the prevalence of h pylori and the presence of vaca/caga genotypes in the oral cavity of mexican children without dyspeptic symptoms the gingival status was measured, and dental plaque samples () were taken 38% of children were positive for h pylori 16s rrna gene by qpcr.

prevalence of h pylori isolates and genotypes and caga gene Methods: to determine the prevalence of specific genotypes of h pylori, clinical isolate of hpylori obtained from 102 patients through endoscopic biopsies was cultured the caga alleles, icea genotypes were determined by pcr.
Prevalence of h pylori isolates and genotypes and caga gene
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2018.